June 29, 2023
5 Reasons Why NAD Patches Are Better Than IVs

If you have ever got an NAD IV, you’re familiar with the discomfort, inconvenience, pain, and the depth of your pocket you need to reach to “indulge” or rather suffer through while this “miracle molecule” makes it into your bloodstream. Now, if you haven’t had an NAD IV before, this last sentence may have just made you run the other direction. Imagine getting that high-dose pure NAD but without all that inconvenience. No, it’s not a prank, it’s a patch.

NAD patches are a new and innovative way to deliver this essential coenzyme into your bloodstream to boost NAD levels, and hence, overall health and longevity. All that without getting pricked by needles and sitting through hours of discomfort.

What Is NAD And Why Is It Important For Longevity?

NAD (nicotinamide adenine dinucleotide) is a coenzyme that’s present in every cell in the body and plays a crucial role in various biological processes, including energy production, metabolism, and DNA repair. However, studies have found that, from rodents to humans, NAD levels begin to decline in varying tissues at varying rates with age.

As NAD levels drop, researchers have found associations with increased risk of heart disease, Type 2 diabetes, Alzheimer's disease and accelerated aging. 

To combat those consequences, they looked at how supplementation may help replenish the cells’ NAD storage, and they found promising results. 

This study concluded that it does have promise in treating cardiovascular disease, including atherosclerosis, high blood pressure, coronary heart disease, arrhythmias, and heart failure.

Another study, published in the Journal of Neuroinflammation, looked at the impact of NAD+ administration on rats in vitro (in a petri dish) and in vivo (living rats) and found that it improved cognitive function and reduced neuroinflammation. 

NAD precursors such as NMN, NR, and niacin, which are later converted to NAD in the body, are common choices when someone wants to increase and maintain adequate NAD levels over time.

To get a significant boost faster, however, NAD IV’s have been the go-to in the past few years. While it’s become an efficient delivery option, the drawbacks are plenty and make IVs a less ideal option for most people. That’s why NAD patches are a better fit to all. Here are five reasons why NAD patches are better than IVs:


Utilizing a proven method, called iontophoresis, via a medical-grade patch, NAD patches are a painless and non-invasive option to deliver high-dose NAD directly to the bloodstream. It’s highly bioavailable, and you don't have to worry about any needles or discomfort during the treatment. IVs, on the other hand, can often cause nausea, chest pain, or headache and are uncomfortable, especially if you have sensitive veins. The IonLayer patch is a white labeled device from a medical-grade supplier. It’s very important to us to ensure that our customers receive the highest quality patch experience possible, so we made the choice to white label a medical-grade patch that will provide an effective delivery of our NAD+ raw ingredient.


NAD patches are small, discreet, and easy to use. You can wear them throughout the day or night without any discomfort or inconvenience. It’s as easy as covering a wound with a bandaid. You’re not tied to a clinic but free to go about your day while the patch is doing its job. In contrast, IVs require you to sit still for extended periods, often up to four hours, while the treatment is being administered.


NAD patches cost a fraction of the price of IVs because they require fewer resources and personnel to administer. You don't have to spend money on clinic visits or medical staff to set up the treatment. You can easily order the NAD patches online, consult with a medical professional via a tele-visit, and have the six patches at your doorstep in a matter of a few days, making them a convenient and affordable option.

More effective

NAD patches deliver a controlled and consistent dose of the coenzyme into the bloodstream over the course of up to 14 hours. This ensures that your body receives the full 500mg of NAD without any spikes or dips in the concentration. IVs, on the other hand, may cause fluctuations in the concentration of the molecule in your bloodstream, which may lead to suboptimal results.


NAD patches are less likely to cause allergic reactions or other adverse effects compared to IVs. They don't carry the risk of infection, bleeding, or other complications associated with invasive procedures. Iontophoresis is not a new concept. It’s been utilized in the medical realm to administer compounds to help reduce inflammation during physical therapy or rehabilitation. It’s a safe and effective method for treatment delivery. 

Are NAD Patches For You?

Boosting NAD levels is all the buzz right now. Considering all the supporting research in its efficacy, it seems as though it will stick around. Literally…The seamless administration of these patches makes it easy for you to stick to the protocol for best results.

If you’re ready to have more energy and clarity, begin to replenish your NAD levels or even grab a handle on an autoimmune condition, NAD patches are an easy, cost-effective, pain-free and efficient solution. Ditch the needles, save time and money, and simply stick on a patch and go about your day with having the energy you’ve been missing.


NAD+ sounds like a crazy chemical, how do I know this is safe?

Sounds crazy, but without NAD+ there would cease to be life. Your body produces NAD+ naturally from B vitamins and via making energy, so it's not a new or foreign compound to the body. There are also other natural ways to make NAD+, such as through nutrition, exercise, and heat exposure.

Does this have a needle? Does it hurt?

Nope! No needles here. Iontophoresis patches use a small one-time use battery to power the current that pushes the NAD+ across the skin and to the bloodstream. The best part? You don't feel a thing. No tingling, pinching, shocking, zapping and best of all -- no needles.

Why not use NAD supplement precursors?

Precursors to NAD+ have been shown to be effective for some, but many do not experience the benefits of increased NAD+ levels as the amounts are too low. The precursors have to go through many steps, which depending on individual biology, may not be efficient or lead to actually increased levels of NAD+. High dose NAD+ administered directly to the bloodstream, as in IV or iontophoresis applications, leads to a much higher and sustained elevation of serum NAD+ than precursors.

Do I need a prescription for NAD+ Patches?

Yes. The iontophoresis patches contain a small battery-operated device that facilitates the absorption of NAD+ through the skin into the bloodstream. The patches are considered a medical device due to this mechanism and, therefore, are only available by prescription. Our network of physicians will review your intake form, schedule a virtual consult, and will help you decide if IonLayer is a good fit or not for you. Upon their recommendation they will prescribe IonLayer and it will ship from our partner pharmacy straight to your door.

If you have additional questions, feel free to browse through more FAQs on our website.