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High Dose NAD+
No Needles

All of the benefits of high dose prescription strength NAD+ IVs without the needles, all at home, whenever you want, for a fraction of the cost.

Join Ion Layer to get 6 needle-free at-home NAD+ treatments up to $150 off.
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Why is Everyone Taking High Dose NAD+?

The world's top physicians, biohackers, celebrities, and athletes are turning to high dose NAD+ infusions, but why?

NAD+ is a critical coenzyme your body uses to produce energy & regulate key bodily functions. The problem is that as we age the level of NAD+ in our bodies decreases which is associated with the acceleration of your body's aging and most disease processes.

The good news? You can increase it.

Increasing NAD+ levels has been linked with[*] the following benefits:

Boosted Energy & Metabolism

NAD+ has been shown to increase your mitochondria function and ATP production, the "power plant" and energy currency of your cells that drive your energy and metabolism.[*]

Reduced Inflammation

Raising NAD+ status for only one week has shown reduced expression of inflammation markers such as TNFa and IL-6 and has been shown to reduce symptoms of inflammatory autoimmune conditions.[**]

A Better Working Brain

NAD+ pathways have been shown as critical to prevent neuronal degradation, increase neuroplasticity, and counteract processes that lead to cognitive decline seen in Alzheimer’s and Parkinson’s.[*]

Improved Performance & Recovery

Increasing NAD+ levels in mice has been shown to increase endurance, capacity, stem cells, and regeneration of skeletal muscle tissue.[*]

Improved Longevity

NAD+ levels decline as you age. This decline is linked to age-related diseases like cognitive decline, cancer, metabolic disease, and frailty. Many of these processes have been shown to slow or even reverse by restoring NAD+ levels.[*]

Better DNA Repair

DNA damage has been linked to a variety of diseases and aging. NAD+ status improvement has been shown to increase angiogenesis, DNA repair and synthesis, and liver regeneration.[**]

Increase Your NAD+ Levels up to 48% in Just 7 Days

Ion Layer has been shown to increase intracellular NAD+ levels up to 48% in just 7 days.

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Definition of Categories [*]
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Ion Layer Community

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I just used the 5th one yesterday and it has made a massive difference. I’ve had some lingering injuries and they instantly feel better when I have the patches on. I feel more energetic, even the days I’m not wearing them. I’m sleeping better.

Brianna D.

NAD therapy helped me recover from COVID. Ion Layer NAD patches are a great alternative to IVs because they are much cheaper and faster.

Dr. Molly M

It’s crazy, my recovery days have been S**t since preseason started and even after a 24 hour travel day, missing a night of sleep, I woke up in the green on my Whoop after wearing the patch! Omar G. 

Omar G.

The patches are pretty damn incredible. Biggest notice is the sustainable energy throughout the day.

Blaine M

I’ve been using these NAD patches for about a year but have been working with NAD for years - after trying so many different options these have become for me by far the best option.

Todd S.

What people are saying

“Ion is the only treatment that has helped reverse my debilitating fatigue. I got very sick from Lyme disease, co-infections & mycotoxin illness in 2019 which caused terrible fatigue. I went from hardly able to care for my son, cook dinner, or run an errand to being able to be on my feet almost all day. My husband was gone when I started and was amazed at the change when he came home. Ion gives me the ability to be a mom and wife again. I’m so grateful.”

Brianna D.


“One of my friends (a VC) noticed how well I was performing in a recent meeting and asked for my secret. I rolled up my sleeve to reveal IonLayer. Ion’s been great. Subtle not-tired feeling all day long, I just feel like I can tackle more on days I’m wearing it.”

Drew S.


“NAD is better than any antidepressant I’ve ever taken. I feel like a weight has been lifted off of me. I just went 6 days straight (loading dose) and by day 4 I was in a new place. Wish I could just take it every day. Calm, happy, energetic in a good not cracked out way”

Justin E.


“As a CrossFit Athlete I am always thinking of ways I can optimize my performance. I believe with Ion Layer I have found that extra edge. When wearing the patches + few days after, I noticed not only strength gains but also my ability to recover aerobically between workouts was significantly improved. The same goes for my sleep and sex drive. I saw benefits across the board!”

Tony S.


“I can almost use Ion Layer like a nootropic and one patch gives me a full day of focus that’s sharp.”

Sameem R.


“Definitely notice the reduction in inflammation, and faster recovery, while wearing it.Stretching feels so much better with it, not painful anymore 👍🏼”

Steve M.


“My experience with IonLayer and their NAD+ product has been nothing short of exceptional. It’s an affordable and astoundingly easy kit to use — no more needles! The results have been remarkable, to say the least. My mind is clearer, more focused, and I’m surprised to discover that my cravings (years-long sugar addict) have all but disappeared! Consequently, my weight is melting off, I have a sustained and an increased level of energy, and I am feeling more vital than I have in years.”

Julien A.


“After 3 days of application I feel great. I feel like I got my young brain back!”

George C.


“Ok great news. Started my second patch and I have killer HD vision this afternoon”

Tony S.

Ion layer

By utilizing our iontophoresis transdermal patches and our high potency at-home activation of NAD+, we're able to provide a non-invasive process to replenish and increase bioavailability of NAD+ in your body.

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No More Needles

You shouldn't have to get a needle stuck in your arm to get the benefits of high dose NAD+ and now you don't with our transdermal iontophoresis patches.

Use Anywhere, at Anytime

No being stuck to an IV bag and tubes. Apply your IonLayer patch like a bandaid and go about normal day to day activities while getting a steady drip of NAD+.

No More Queasy Reactions

NAD+ IVs notoriously lead to cramping and nausea. Our patches deliver NAD+ over 14 hours so you barely feel any reaction to high doses.

High Dose NAD+

Supplement NAD+ precursors like don't supply your body with NAD+ directly. Each IonLayer patch delivers more bioactive NAD+ than most IVs straight to your bloodstream.

Cheaper than IVs

Most NAD+ IVs cost $750+ per 500mg infusion and over $4k for a 6-pack of IVs. Our IonLayer patches are a fraction of the cost so you can use prescription strength NAD+ to reach all of your health goals.

Maximum Bioavailability

Our NAD+ is shipped in its raw state and mixed with sterile water immediately before use, to ensure maximum effectiveness and bioavailability.

Secure Your Spot
Apply to Join Ion Layer

Ion Layer spots are limited and by invite only. Secure your spot by ordering your Ion Kit today.

Ion Layer offers a 💯% money-back guarantee within 30 days of purchase if not satisfied.
How Ion Layer Works
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NAD+ patches

Frequently Asked Questions



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What is NAD+?

It is a coenzyme that is critical for every cell in your body and the majority of your metabolic processes. It carries electrons around your body that are critical for energy, metabolism, DNA repair, and more. It is critical for life and buffers many physiological processes. As you age and succumb to inflammatory processes, natural NAD+ production decreases.

Why do I have to mix my NAD+ in vials?

NAD+ starts degrading as soon as it is made into a solution. If you'd had any NAD+ that isn't mixed right before you use it, you are likely getting a very low amount, if at all of the active compounds. We supply your raw NAD+ with sterile water to maximize the potency to make sure you get the most out of your treatment as humanly possible.

NAD+ sounds like a crazy chemical, how do I know this is safe?

Sounds crazy, but without NAD+ there would cease to be life. Your body produces NAD+ naturally from B vitamins and via making energy, so it's not a new or foreign compound to the body. There are also other natural ways to make NAD+, such as through nutrition, exercise, and heat exposure.

Does this have a needle? Does it hurt?

Nope! No needles here. Iontophoresis patches use a small one-time use battery to power the current that pushes the NAD+ across your skin and to your bloodstream. The best part? You don't feel a thing. No tingling, pinching, shocking, zapping and best of all -- no needles.

Why not use NAD supplement precursors?

Precursors to NAD+ have been shown to be effective for some, but many do not experience the benefits of increased NAD+ levels as the amounts are too low. The precursors have to go through many steps, which depending on individual biology, may not be efficient or lead to actually increased levels of NAD+. High dose NAD+ administered directly to the bloodstream, as in IV or iontophoresis applications, leads to a much higher and sustained elevation of serum NAD+ than precursors.

Do I need a prescription for NAD+ Patches?

Yes. The iontophoresis patches contains a small battery operated device that facilitates the absorption of NAD+ through skin into the bloodstream. The patches are considered a medical device due to this mechanism and, therefore, are only available by prescription. Our network of physicians will review your intake form, schedule a virtual consult, and will help you decide if IonLayer is a good fit or not for you. Upon their recommendation they will prescribe IonLayer and it will ship from our partner pharmacy straight to your door.

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Ion Layer is certified by LegitScript. LegitScript is widely recognized as the leading provider of certification and monitoring services for products and companies like Ion Layer. They monitor millions of websites and merchants and inform governments, and the public about legitimate and trustworthy products and companies. Many view their seal of approval as a benchmark for quality and safety as LegitScript ensures a rigorous certification process.
See our LegitScript Certification

Supercharge your

Apply to join the Ion Layer NAD+ program to supercharge your mitochondrial health.
Apply the Ion Layer patch and feel it work. Wear it for 14 hours while you go about your day.
Feel & perform your best with your body's new supercharged mitochondria.

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